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Three decades ago, Congress set up a system to encourage drug companies to develop treatments for rare diseases. The law has worked, but at a high cost.

The Los Angeles County Medical Examiner said that it has received notification of 10 fire-related deaths as firefighters battle multiple blazes for a third consecutive night.

Infantryman Robert Kotlowitz was one of only three in his platoon to survive an ill-advised attack on the Germans. Robert Williams served with the Tuskegee Airmen. Originally broadcast in '99 and '95.

In Lebanon, a reconstructive surgeon who specializes in helping children recover from war wounds meets with a 6-year-old girl who lost her arm to an explosion in Gaza nearly two years ago.

On the heels of the final presidential debate and with less than two weeks until Election Day, both President Obama and Mitt Romney are sprinting to the finish. Political Junkie Ken Rudin talks about the takeaways from the debates and the challenges facing each campaign in the homestretch.

A record number of visitors flocked to the Buffalo and Erie County Botanical Gardens this weekend for the blossoming of the "corpse flower" Morty.The…

China Unicom's tailor has set up a sewing machine, ready to alter concerned customers' pants so that the larger version of the phone will fit in their pockets.

Buffalo Public School students were on their way to the bus stops Wednesday morning when schools superintendent Pamela Brown canceled most classes. With…

Just weeks before the November 6 election, outgoing Seneca Nation of Indians President Robert Odawi Porter and other Nation officials are raising concerns…

A lake effect snow storm battered the Metro Buffalo area late Thursday afternoon, just as the evening commute was getting underway. The heavy snowfall…