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A dangerous chemical called xylazine is being mixed into fentanyl across the U.S., but who's doing it and why is a mystery. The government still doesn't identify and track new drug threats.

British singer, songwriter and guitarist Lowe got his start in the '70s pub-rock era. His 2001 album, The Convincer, has been newly remastered and reissued. Originally broadcast in 2001 and 2011.

Mellencamp had big hits in the '80s, including "Jack and Diane" and "Small Town." He performed "Pink Houses" for Obama's inaugural concert. Mellencamp joins us to talk about his life and music.

The U.S. is giving $1.6 million to researchers to study how the hepatitis B vaccine affects newborns in Guinea-Bissau. After an outcry, the future of the trial is up in the air.

New York Times journalist Eric Schmitt says the president's threats against Iran and his recent purge at the Pentagon, in which he ousted his secretary of defense, could undermine national security.

For the better part of a decade, Nicki simply existing as Nicki felt like a radical act. Along the way, things changed: rap, the internet, fandom, feminism. Maybe Minaj did, too.

When guitarist Mato Nanji made backstage conversation about the history of his tribe, the Nakota nation, he didn't expect his comments to inspire trance bluesman Otis Taylor. Host Michel Martin speaks to the two musicians behind the new album 'My World is Gone.'

Donald Berwick resigned as administrator of the Centers for Medicare and Medicaid Services in December. Berwick explains why he thinks much of the spending in the U.S. health care system is wasted, and the need to reform Medicare and Medicaid to improve coordination of care.

NPR's list of memorable visual stories includes coverage of the 2018 midterm election, migrant caravans, Puerto Rico's hurricane recovery and, of course, a musical insect invasion.

Attorney General Jeff Sessions is set to appear before members of Congress amid a war of credibility between the administration and former FBI Director James Comey.