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Tuesday night's guest star just wants to have some fun behind the Tiny Desk. She'll revisit her classics and perform new songs from her album Threads.

Hamburg-born Astrid Kirchherr met the Beatles in 1960, before they were famous. She took some of the earliest photographs of the group and was engaged to Stuart Sutcliffe, the Beatles' original bassist, before he died of a brain hemorrhage in 1962.

Instead of adding hot water to brown dust with freeze-dried marshmallows, NPR's Steve Inskeep decided to learn how to do hot chocolate right. Pastry chef David Guas walks Inskeep through his recipe for Mexican hot chocolate, which features vanilla beans, almond extract and cinnamon.

Mad cow disease and related illness are thought to be spread by an infectious protein, not a germ. But some prominent scientists don't agree. NPR's Richard Harris travels to a National Institutes of Health lab in Montana, where a group of scientists have been trying for several decades to get to the bottom of brain-wasting diseases.

The federal Drug Enforcement Administration has begun a new initiative aimed at combating the rising rates of drug-related violent crime and overdose deaths plaguing American communities.

Carl Hancock Rux began his career in the arts as a spoken-word poet. He has ambitiously matured into an author, musician and playwright. Rux discusses his new novel, Asphalt, and his CD, Apothecary Rx.

When it comes to awards in theater or television or dance or literature, Frank Deford observes, candidates don't worry about losing out because of a personal flaw. Only sports applies that off-the-field standard.

The film premieres on HBO Saturday.

After a tough year for the film industry, we were lucky to still get to see some great movies this year. We talk about the best ones and unpack what we think is ahead in 2021.

NPR's Ayesha Rascoe plays the puzzle with listener, Karen Brock, and puzzlemaster, Will Shortz.